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Current Issue

2016: 116/6 (Dec) pp. 1003–1181

Journal: Thrombosis and Haemostasis
ISSN: 0340-6245

21 articles
1.
Managing reversal of direct oral anticoagulants in emergency situations
Anticoagulation Education Task Force White Paper

W. Ageno (1), H. R. Büller (2), A. Falanga (3), W. Hacke (4), J. Hendriks (5, 6), T. Lobban (7), J. Merino (8), I. S. Milojevic (9), F. Moya (10), H. B. van der Worp (11), G. Randall (12), K. Tsioufis (13), P. Verhamme (14), A. J. Camm (15, 16)

(1) University of Insubria, Varese, Italy; (2) Academic Medical Centre, Amsterdam, The Netherlands; (3) Department of Immunohematology & Transfusion Medicine and the Hemostasis and Thrombosis Center, Hospital Papa Giovanni XXIII, Bergamo, Italy; (4) Department of Neurology, Heidelberg University, Heidelberg, Germany; (5) Centre for Heart Rhythm Disorders, University of Adelaide, Royal Adelaide Hospital, South Australian Health & Medical Research Institute, Adelaide, Australia; (6) Department of Medical and Health Sciences, Linköping University, Linköping, Sweden; (7) Arrhythmia Alliance and AF Association, Hampshire, UK; (8) Arrhythmia Research Unit, Universitario La Paz , Madrid, Spain; (9) General Hospital Cuprija, Cuprija, Serbia; (10) International Medical Services and Emergency Medicine, Vithas-Xanit International Hospital, Benalmadena, Malaga, Spain; (11) Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands; (12) Stroke Alliance For Europe (SAFE), London, UK; (13) First Cardiology Clinic, Hippokration Hospital, University of Athens, Greece; (14) University of Leuven, Leuven, Belgium; (15) Division of Cardiovascular Sciences, St George’s University of London, London, UK; (16) ICMS, Imperial College, London, UK

Thromb Haemost 2016 116 6: 1003-1010

http://dx.doi.org/10.1160/TH16-05-0363

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2.
New genetic association for the kinin system: the L-arginine connection
Insight: association of L-arginine levels and two loci in genes of the kallikrein-kinin system

See also Zhang et al.

P. García de Frutos (1), J. Martínez-González (2)

(1) Department of Cell Death and Proliferation, IIBB-CSIC and IDIBAPS, Barcelona, Spain; (2) Centro de Investigación Cardiovascular (CSIC-ICCC), Instituto de Investigación Biomédica Sant Pau (IIB-Sant Pau), Barcelona, Spain

Thromb Haemost 2016 116 6: 1011-1011

http://dx.doi.org/10.1160/TH16-11-0826

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3.

R. De Caterina (1), E. D'Ugo (1), P. Libby (2)

(1) “G. d’Annunzio” University and Center of Excellence on Aging, Chieti, Italy; (2) Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

Thromb Haemost 2016 116 6: 1012-1021

http://dx.doi.org/10.1160/TH16-03-0246

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4.

Y. Takagi (1, 2), M. Murata (1), T. Kozuka (1), Y. Nakata (1), R. Hasebe (1), S. Tamura (1), A. Takagi (1), T. Matsushita (3), H. Saito (4), T. Kojima (1)

(1) Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan; (2) Japan Society for the Promotion of Science, Tokyo, Japan; (3) Department of Transfusion Medicine, and Nagoya University Hospital, Nagoya, Japan; (4) Nagoya National Hospital, Nagoya, Japan

Thromb Haemost 2016 116 6: 1022-1031

http://dx.doi.org/10.1160/TH16-03-0223

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5.

X. Zhou (1), M. L. V. Hendrickx (1), G. Hassanzadeh-Ghassabeh (2, 3), S. Muyldermans (2), P. J. Declerck (1)

(1) Laboratory for Therapeutic and Diagnostic Antibodies, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Belgium; (2) Cellular and Molecular Immunology, Faculty of Science and Bio-engineering Sciences, Vrije Universiteit Brussel, Brussels, Belgium; (3) Nanobody Service Facility, VIB, Brussels, Belgium

Thromb Haemost 2016 116 6: 1032-1040

http://dx.doi.org/10.1160/TH16-04-0306

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6.

Online Supplementary Material

See also García de Frutos, Martínez-González

W. Zhang (1, 2), F. Jernerén (3), B. C. Lehne (1), M.-H. Chen (4), R. N. Luben (5), C. Johnston (3), A. Elshorbagy (3, 6), R. N. Eppinga (7, 8), W. R. Scott (1, 9), E. Adeyeye (2, 10), J. Scott (9), R. H. Böger (11), K.-T. Khaw (5), P. van der Harst (7, 8), N. J. Wareham (12), R. S. Vasan (13, 14), J. C. Chambers (1, 2, 15), H. Refsum (3, 16), J. S. Kooner (2, 9, 15)

(1) Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK; (2) Department of Cardiology, Ealing Hospital NHS Trust, Uxbridge Road, Southall, UK; (3) Department of Pharmacology, University of Oxford, Oxford, UK; (4) Population Sciences Branch, National Heart, Lung, Blood Institute, National Institutes of Health, Framingham, Massachusetts, USA; (5) Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK; (6) Department of Physiology, Faculty of Medicine, University of Alexandria, Alexandria, Egypt; (7) Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands; (8) Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; (9) National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, London, UK; (10) Faculty of Medicine, Imperial College London, South Kensington Campus, London, UK; (11) Department of Clinical Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; (12) Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, UK; (13) Section of Preventive Medicine and Epidemiology and Cardiology, Boston University School of Medicine, Boston, Massachusetts, USA; (14) Boston University and National Heart, Lung & Blood Institute’s Framingham Heart Study, Framingham Massachusetts, USA; (15) Imperial College Healthcare NHS Trust, London, UK; (16) Department of Nutrition, Institute of Basic Medical Science, Faculty of Medicine, University of Oslo, Oslo, Norway

Thromb Haemost 2016 116 6: 1041-1049

http://dx.doi.org/10.1160/TH16-02-0151

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7.

Online Supplementary Material

O. Eriksson (1), A. Asplund (2), G. Hegde (3), P.-H. Edqvist (2), S. Navani (3), F. Pontén (2), A. Siegbahn (1)

(1) Department of Medical Sciences, Clinical Chemistry and Science for Life Laboratory, Uppsala University, Uppsala, Sweden; (2) Department of Immunology, Genetics and Pathology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden; (3) Lab Surgpath, The Human Protein Atlas Project, Mumbai Site, Mumbai, India

Thromb Haemost 2016 116 6: 1050-1059

http://dx.doi.org/10.1160/TH16-04-0267

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8.

Online Supplementary Material

F. Rollini (1), F. Franchi (1), K. Singh (1), J. R. Cho (1), M. Bhatti (1), C. DeGroat (1), J. Hu (1), N. Aggarwal (1), Z. Alobaidi (1), E. Thano (1), E. Ferrante (1), M. Zenni (1), T. A. Bass (1), D. J. Angiolillo (1)

(1) University of Florida College of Medicine – Jacksonville, Jacksonville, Florida, USA

Thromb Haemost 2016 116 6: 1060-1069

http://dx.doi.org/10.1160/TH16-05-0377

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9.

C. Lavenu-Bombled (1, 2, 3, 4), C. Guitton (5, 3), A. Dupuis (6, 7, 8, 9, 4), M.-J. Baas (6, 7, 8, 9), C. Desconclois (1, 3, 4), M. Dreyfus (1, 3, 4), R. Li (10), C. Caron (11, 3), C. Gachet (6, 7, 8, 9, 4), E. Fressinaud (2, 11, 3), F. Lanza (6, 7, 8, 9, 4)

(1) Service d’Hématologie Biologique, CHU Bicêtre, AP-HP, Université Paris Sud, Le Kremlin Bicêtre, France; (2) INSERM UMR_S1176, Université Paris-Sud, Université Paris-Saclay, Le Kremlin-Bicêtre, France; (3) Centre de Référence de la Maladie de Willebrand, France; (4) Centre de Référence des Pathologies Plaquettaires, France; (5) Service de Rhumato-Hématologie Pédiatrique, CHU Bicêtre, AP-HP, Université Paris Sud, Le Kremlin Bicêtre, France; (6) UMR_S949 INSERM, Strasbourg, France; (7) Etablissement Français du Sang (EFS)-ALCA, Strasbourg, France; (8) Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France; (9) Université de Strasbourg, Strasbourg, France; (10) Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Children’s Healthcare of Atlanta and Emory University School of Medicine, Atlanta, Georgia, USA; (11) Département d’Hématologie Transfusion, CHU Lille, France

Thromb Haemost 2016 116 6: 1070-1078

http://dx.doi.org/10.1160/TH16-06-0438

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10.

A. Björquist (1), C. A. Di Buduo (2, 3), E. A. Femia (4), R. F. Storey (5), R. C. Becker (6), A. Balduini (2, 3, 7), S. Nylander (1), M. Cattaneo (4)

(1) AstraZeneca R&D Mölndal, Sweden; (2) Department of Molecular Medicine, University of Pavia, Pavia, Italy; (3) Biotechnology Research Laboratories, IRCCS San Matteo Foundation, Pavia, Italy; (4) Medicina 3, Ospedale San Paolo – Dipartimento di Scienze della Salute, Università degli Studi di Milano. Milan, Italy; (5) Department of Infection Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK; (6) University of Cincinnati College of Medicine, Heart, Lung and Vascular Institute, Tufts University, Medford, Massachusetts, USA; (7) Department of Biomedical Engineering, Tufts University, Medford, Massachusetts, USA

Thromb Haemost 2016 116 6: 1079-1088

http://dx.doi.org/10.1160/TH15-10-0829

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11.

F. Santilli (1), R. Liani (1), P. Di Fulvio (1), G. Formoso (1), P. Simeone (1), R. Tripaldi (1), T. Ueland (2), P. Aukrust (2), G. Davì (1)

(1) Department of Medicine and Aging, Center of Excellence on Aging, “G. d’Annunzio” University of Chieti, Chieti, Italy; (2) Research Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway

Thromb Haemost 2016 116 6: 1089-1099

http://dx.doi.org/10.1160/TH16-06-0471

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12.

I. Massimi (1), L. V. Lotti (1), F. Temperilli (1), M. Mancone (2), G. Sardella (2), S. Calcagno (2), O. Turriziani (3), L. Frati (4), F. M. Pulcinelli (1)

(1) Department of Experimental Medicine, “Sapienza” University of Rome, Rome, Italy; (2) Department of Cardiovascular, Respiratory, Nephrology, Anesthesiology and Geriatric Sciences, “Sapienza” University of Rome, Rome, Italy; (3) Department of Molecular Medicine, “Sapienza” University of Rome, Rome, Italy; (4) I. R. C. C.S Neuromed, Località Camerelle, Pozzilli (CB), Italy

Thromb Haemost 2016 116 6: 1100-1110

http://dx.doi.org/10.1160/TH16-04-0316

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13.

Online Supplementary Material

R. N. Tunjungputri (1, 2), E. Peters (3, 4), A. van der Ven (1), P. G. de Groot (5), Q. de Mast (1, 5), P. Pickkers (3)

(1) Department of Internal Medicine, Radboud university medical center, Nijmegen, The Netherlands; (2) Center for Tropical and Infectious Diseases (CENTRID), Faculty of Medicine Diponegoro University - Dr. Kariadi Hospital, Semarang, Indonesia; (3) Department of Intensive Care Medicine, Radboud university medical center, Nijmegen, The Netherlands; (4) Department of Pharmacology and Toxicology, Radboud university medical center, Nijmegen, The Netherlands; (5) Department of Clinical Chemistry and Haematology, University Medical Centre, Utrecht, The Netherlands

Thromb Haemost 2016 116 6: 1111-1121

http://dx.doi.org/10.1160/TH16-03-0206

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14.

S. Yakovlev (1, 2), A. M. Belkin (1, 2, 3), L. Chen (4, 5), C. Cao (1, 5), L. Zhang (1, 5), D. K. Strickland (1, 5, 6), L. Medved (1, 2)

(1) Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, Maryland, USA; (2) Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland, USA; (3) Present address: Center for Scientific Review, National Institutes of Health, Bethesda, Maryland, USA; (4) Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA; (5) Department of Physiology, University of Maryland School of Medicine, Baltimore, Maryland, USA; (6) Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland, USA

Thromb Haemost 2016 116 6: 1122-1130

http://dx.doi.org/10.1160/TH16-04-0333

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15.

Online Supplementary Material

L. Friberg (1), M. Skeppholm (1)

(1) Karolinska Institute, Department of Clinical Sciences at Danderyd Hospital, Stockholm, Sweden

Thromb Haemost 2016 116 6: 1131-1139

http://dx.doi.org/10.1160/TH16-05-0400

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16.
Open Access

Online Supplementary Material

M. Koziński (1), M. Ostrowska (1), P. Adamski (1), J. Sikora (2), A. Sikora (3), A. Karczmarska-Wódzka (2), M. P. Marszałł (3), J. Boinska (4), E. Laskowska (1), E. Obońska (2), T. Fabiszak (5), J. Kubica (5)

(1) Department of Principles of Clinical Medicine, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland; (2) Department of Pharmacology and Therapy, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland; (3) Department of Medicinal Chemistry, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland; (4) Department of Pathophysiology, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland; (5) Department of Cardiology and Internal Medicine, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland

Thromb Haemost 2016 116 6: 1140-1149

http://dx.doi.org/10.1160/TH16-07-0535

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17.

W. Darwiche (1), T. Bejan-Angoulvant (1), D. Angoulvant (1), D. Babuty (1), L. Fauchier (1)

(1) Cardiologie, Pole Cœur Thorax Vasculaire, Centre Hospitalier Universitaire Trousseau et Faculté de Médecine, Université Francois Rabelais, Tours, France

Thromb Haemost 2016 116 6: 1150-1158

http://dx.doi.org/10.1160/TH16-06-0483

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18.

S. M. Bleker (1), A. T. Cohen (2), H. R. Büller (1), G. Agnelli (3), A. S. Gallus (4), G. E. Raskob (5), J. I. Weitz (6), M. Curto (7), M. Sisson (7), S. Middeldorp (1)

(1) Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands; (2) Guy’s and St Thomas’ Hospitals, King’s College, London, UK; (3) Division of Internal and Cardiovascular Medicine, Stroke Unit, University of Perugia, Perugia, Italy; (4) SA Pathology at Flinders Medical Centre & Flinders University, Adelaide, Australia; (5) College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA; (6) McMaster University and Thrombosis and Atherosclerosis Research Institute, Hamilton, Canada; (7) Pfizer Inc., Groton, Conneticut, USA

Thromb Haemost 2016 116 6: 1159-1164

http://dx.doi.org/10.1160/TH16-02-0137

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19.

Online Supplementary Material

C. Carrera (1), J. Jiménez-Conde (2), S. Derdak (3), K. Rabionet (4), C. Vives-Bauzá (5), C. Soriano-Tárrega (2), E. Giralt-Steinhauer (2), M. Mola-Caminal (2), R. M. Diaz-Navarro (6), S. Tur (6), E. Muiño (7), C. Gallego-Fabrega (7), S. Beltran (3), J. Roquer (2), A. Ruiz (8), O. Sotolongo-Grau (8), J. Krupinski (9), J.-M. Lee (10), C. Cruchaga (10), P. Delgado (1), R. Malik (11), B. B. Worrall (12), S. Seshadri (13), J. Montaner (1), I. Fernández-Cadenas (7), on behalf of the Metastroke Consortium, ISGC Consortium and Genestroke Consortium

(1) Neurovascular Research Laboratory, Valld’Hebron Institute of Research, Universitat Autonoma de Barcelona, Barcelona, Spain; (2) Department of Neurology, Neurovascular Research Group, IMIM-Hospital del Mar (Institut Hospital del Mar d’Investigacions Mediques), Universitat Autonoma de Barcelona/DCEXS-Universitat Pompeu Fabra, Barcelona, Spain; (3) National Center for Genome Analysis, CNAG, Barcelona, Spain; (4) Center for Genomic Regulation, IMIM, Barcelona, Spain; (5) Research Unit, Son Espases University Hospital, IdISPa, Palma de Mallorca, Spain; (6) Neurology Department, Son Espases University Hospital, IdISPa, Palma de Mallorca, Spain; (7) Stroke Pharmacogenomics and Genetics, Fundacio Docencia i Recerca Mutua Terrassa, Mutua de Terrassa Hospital, Terrassa (Barcelona), Spain; (8) ACE Foundation, Institut Català de Neurociències Aplicades, Research Center, Barcelona, Spain; (9) Neurology Unit, Neuroscience Department, Mutua de Terrassa Hospital, Terrassa (Barcelona), Spain; (10) Washington University School of Medicine, St. Louis, Missouri, USA; (11) Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians University, Munich, Germany; (12) Departments of Neurology and Public Health Sciences, University of Virginia, Charlottesville, Virginia, USA; (13) Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA

Thromb Haemost 2016 116 6: 1165-1171

http://dx.doi.org/10.1160/TH16-02-0113

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20.

J. I. Weitz (1), S. Haas (2), W. Ageno (3), P. Angchaisuksiri (4), H. Bounameaux (5), J. D. Nielsen (6), S. Z. Goldhaber (7), S. Goto (8), G. Kayani (9), L. Mantovani (10), P. Prandoni (11), S. Schellong (12), A. G. G. Turpie (13), A. K. Kakkar (9, 14)

(1) McMaster University and the Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canada; (2) Formerly: Technical University of Munich, Munich, Germany; (3) University of Insubria, Varese, Italy; (4) Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; (5) Division of Angiology and Hemostasis, University Hospitals of Geneva, Switzerland; (6) Bispebjerg-Frederiksberg Hospital, Copenhagen, Denmark; (7) Harvard Medical School, Boston, Massachusetts, USA; (8) Tokai University, Kanagawa, Japan; (9) Thrombosis Research Institute, London, UK; (10) University of Milano-Bicocca, Milan, Italy; (11) University of Padua, Padua, Italy; (12) Municipal Hospital Friedrichstadt, Dresden, Germany; (13) McMaster University, Hamilton, Canada; (14) University College London, London, UK

Thromb Haemost 2016 116 6: 1172-1179

http://dx.doi.org/10.1160/TH16-04-0335

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