Contact Person

Dr. Elinor Switzer

Managing Editor

Phone: +49 (0)711 - 8931-230
Fax: +49 (0)711 - 8931-323
send an Email


Air travel and fatal pulmonary embolism

Journal: Thrombosis and Haemostasis
ISSN: 0340-6245
Issue: 2006: 95/5 (May) pp. 755-916
Pages: 807-814

Air travel and fatal pulmonary embolism

Lianne Parkin, Melanie L. Bell, G. Peter Herbison, Charlotte Paul, David C. G. Skegg
Department of Preventive and Social Medicine, University of Otago, New Zealand


pulmonary embolism, clinical / epidemiological studies


Although long-distance air travel is commonly regarded as a risk factor for venous thromboembolism, the risk of clinically important events has not been well defined.We estimated the absolute risk of dying from pulmonary embolism following longdistance air travel in a national population-based descriptive study of 121 men and women who were aged 15–59 years (the age range in which the majority of international arrivals are found) and whose underlying cause of death was certified as codes 415.1, 451, or 453 of the International Classification of Diseases (ninth revision). Eleven cases had undertaken longdistance air travel in the four weeks before the onset of the fatal episode. The estimated risks of fatal pulmonary embolism following a flight of at least three hours’ duration were 0.5 (95% CI 0.2–1.2) and 0.6 (95% CI 0.2–1.4) per million arrivals for overseas visitors and New Zealand residents, respectively. For air travel of more than eight hours’ duration, the risk in New Zealand residents was 1.3 (95% CI 0.4–3.0) per million arrivals.We also conducted a case-control study based on those cases who were normally resident in New Zealand and registered on the electoral roll (n=99 ). For each case, four controls matched for sex, age, and electorate, were randomly selected from the electoral roll. In the key analysis (based on 88 cases and 334 controls), the adjusted odds ratio for travellers who had flown for more than eight hours was 7.9 (95% CI 1.1–55.1) compared with those who did not undertake a long-distance flight. Longdistance air travellers have a higher risk of dying from pulmonary embolism than non-travellers, but the absolute risk in people aged 15–59 years appears to be very small.

You may also be interested in...

Mats Ögren1 , David Bergqvist1 , Karin Wåhlander2 , Henry Eriksson2 , Nils H. Sternby 3

Thromb Haemost 2006 95 3: 541-545

H. Partsch

Phlebologie 2003 32 2: 29-36

H. Leon Daneschvar 1, Ali Seddighzadeh 1, Gregory Piazza 2, Samuel Z. Goldhaber1

Thromb Haemost 2008 99 6: 1035-1039